St. Columban is located on the Clermont County side of Loveland, OH near the corner of Wards Corner Road and Oakland Road (State Route 48).
From downtown Loveland Follow W. Loveland Avenue to State Route 48. Turn right and at the next stop sign turn left, following SR 48. At the stop light, turn left and the church will be on your left.
From Interstate 275 Exit at Wards Corner Road (exit 54). Go east on Wards Corner Road approximately 3 1/2 miles until you reach a stop light at the intersection with SR 48. Turn right onto SR 48 and the church will be on your left.